GeneFisher–Software Support for the Detection of Postulated Genes

Proceedings Of The Fourth International Conference On Intelligent Systems For Molecular Biology

Volume

Proceedings Of The Fourth International Conference On Intelligent Systems For Molecular Biology

Contents

When a family of genes from closely related organisms is known, there is a certain chance to extract the corresponding gene from the genome of another related organism. This can be done by polymerase chain reaction, provided that a pair of suitable primers can be designed. In contrast to primer design for a single, known target sequence, systematic primer design for an unknown target given a group of homologues can by no means be done manually. GcneFisher is a software tool which automates this task, and takes special care to make the impact of the manifold design parameters transparent to the user.