Automatic Extraction of Biological Information from Scientific Text: Protein-Protein Interactions

Proceedings Of The Seventh International Conference On Intelligent Systems For Molecular Biology

Volume

Proceedings Of The Seventh International Conference On Intelligent Systems For Molecular Biology

Contents

We describe the basic design of a system for automatic detection of protein-protein interactions extracted from scientific abstracts. By restricting the problem domain and imposing a number of strong assumptions which include pre-specified protein names and a limited set of verbs that represent actions, we show that it is possible to perform accurate information extraction. The performance of the system is evaluated with different cases of real-world interaction networks, including the Drosophila cell cycle control. The results obtained computationally are in good agreement with current biological knowledge and demonstrate the feasibility of developing a fully automated system able to describe networks of protein interactions with sufficient accuracy.