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Proceedings of the Twentieth International Conference on Machine Learning, 1995
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Proceedings of the Twentieth International Conference on Machine Learning, 1995
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Abstract:
With the growing number of known 3D protein structures, computing systems, that can predict where two protein molecules interact with each other are becoming of increasing interest. A system is presented, integrating preprocessing like the computation of molecular surfaces, segmentation, and searching for complementarity in the general framework of a pattern analyzing semantic network (ERNEST). The score of coarse symbolic computations is used by the problem independent control strategy of ERNEST to guide a more detailed analysis considering steric clash and judgements based on grid--based surface representations. Successfull examples of the docking system are discussed that compare well with other approaches.
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Proceedings of the Twentieth International Conference on Machine Learning, 1995