Frank Tobin and Igor Goryanin

The mathematical modeling of very large biological pathways presents serious computational challenges. Current techniques will no longer be adequate owing to their lack of scalability. Some of the resulting challenges are mathematical. Many of them arise from the knowledge representation, ambiguity, the qualitative nature the information, and the lack of enough information. This talk will describe the steps in the underlying modeling problem and the changes that occur as the pathways become large. There are computational challenges, but opportunities to incorporate artificial intelligence techniques into what has traditionally been a purely mathematical problem.