A Computational Model of Reasoning from the Clinical Literature

Authors

  • Glenn D. Rennels
  • Edward H. Shortliffe
  • Frank E. Stockdale
  • Perry L. Miller

DOI:

https://doi.org/10.1609/aimag.v10i1.728

Abstract

This article explores the premise that a formalized representation of empirical studies can play a central role in computer- based decision support. The specific motivations underlying this research include the following propositions: (1) Reasoning from experimental evidence contained in the clinical literature is central to the decisions physicians make in patient care. (2) A computational model based on a declarative representation for published reports of clinical studies can drive a computer program that selectively tailors knowledge of the clinical literature as it is applied to a particular case. (3) The development of such a computational model is an important first step toward filling a void in computer-based decision support systems. Furthermore, the model can help us better understand the general principles of reasoning from experimental evidence both in medicine and other domains. Roundsman is a developmental computer system that draws on structured representations of the clinical literature to critique plans for the management of primary breast cancer. Roundsman is able to produce patient-specific analyses of breast cancer-management options based on the 24 clinical studies currently encoded in its knowledge base. The Roundsman system is a first step in exploring how the computer can help bring a critical analysis of the relevant literature, structured around a particular patient and treatment decision, to the physician.

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Published

1989-03-15

How to Cite

Rennels, G. D., Shortliffe, E. H., Stockdale, F. E., & Miller, P. L. (1989). A Computational Model of Reasoning from the Clinical Literature. AI Magazine, 10(1), 49. https://doi.org/10.1609/aimag.v10i1.728

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Section

Articles