John Mark Agosta and Jonathan S. Katz
Medical practitioners are pragmatic about defining new diseases to explain rarely occurring combinations of symptoms. This paper reviews a case from the literature that introduced a new disease by comparing two Bayes network diagnostic models, one that contains the disease, the other a sub-model without it. The analysis shows how the measure of evidence conflict proposed by Jensen 1990 applies in the case of a diagnosis where conflict appears as the disease progresses. We demonstrate how such a model with a known set of diseases can be extended to include a new disease.