R. Bellazzi, C. Siviero, M. Stefanelli, G. de Nicolao, and A. Bellazzi
In the Insulin Dependent Diabetes Mellitus (I type diabetes), the insufficient insulin production impairs the closed-loop insulin/glucose regulation system. Diabetic patients need exogenous insulin in order to restore the correct glucose metabolism. The challenging problem of managing diabetic patients is essentially a long term control problem, whose goals are to normalize the Blood Glucose Levels (BGL) and to avoid hyperglycemic peaks and hypoglycemic episodes. Although this task is very complex, involving various factors, as patient’s life-style and treatment compliance, we have chosen the diabetes problem as a benchmark for the definition of a novel methodology for intelligent patient monitoring based on adaptive controllers.